Karen, Scottsdale AZ
“My neck looked 20 years older than my face, and I’d tried every neck cream at the drugstore. Three weeks in, the crinkly lines under my chin are softer and I’ve stopped pulling my collar up.”
4.8/5, 13,286 Verified Reviews
Avena NAD+ Peptide Serum
Helps smooth the look of crepey skin on your neck, chest and arms
Skin looks firmer and feels softer, in weeks, not months
Lightweight, soaks in within seconds, never greasy on your clothes
NAD+, 14 peptides and 5 ceramides in one step
FREE SHIPPING ON EVERY BUNDLE
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Most women take the 28-day supply, because week three is when the neck starts to change. The 2-month supply is the lowest price per bottle: $29.75.
How does it work?
The skin on your neck, chest and arms is thinner than the skin on your face, and it has been ignored for years. When it dries out and loses its bounce, it folds into those fine crinkles.
This serum puts back what that skin is missing:
14 peptides — help skin look firmer and smoother, so the crinkles look softer.
5 ceramides — help rebuild the moisture barrier, so skin stays soft instead of drying back out by lunch.
8 forms of hyaluronic acid — pull water into the skin at different depths, so it looks plumper.
NAD+ — a coenzyme your skin already uses, here to help tired-looking skin look fresh again.
Lightweight base — soaks in within seconds, so you can get dressed straight away.
How long until I see a difference?
Most women feel it on day one: soft, hydrated skin with nothing sticky left behind.
Skin looks smoother within the first week. The crinkly look on the neck and chest softens around week three, which is why the 28-day supply is the one most people start with.
How do I use it?
Morning and night, on clean skin. Warm 3 or 4 drops between your fingers and sweep them up your neck, from the collarbone to the jaw.
Then a few more across your chest and the backs of your arms. Wear sunscreen in the daytime.
One 30 ml bottle is a 14-day supply used this way.
Ingredients
| NAD+ | Nicotinamide Adenine Dinucleotide |
| Peptides | 14, incl. Copper Tripeptide-1 |
| Ceramides | NP, NS, AS, AP, EOP |
| Hyaluronic acid | 8 forms |
| Also | Niacinamide, squalane, shea butter |
| Size | 30 ml / 1.01 fl oz |
Full list: Aqua/Water/Eau, Butylene Glycol, Glycerin, Cetyl Ethylhexanoate, 1,2-Hexanediol, Niacinamide, Hydrogenated Lecithin, Pentaerythrityl Tetrabehenate, Betaine, Diethoxyethyl Succinate, Nicotinamide Adenine Dinucleotide, Nicotinamide Mononucleotide, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Oligopeptide-32, Oligopeptide-29, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Octapeptide-3, Palmitoyl Tetrapeptide-7, Oligopeptide-6, Soluble Collagen, Ceramide NP, Ceramide NS, Ceramide AS, Ceramide AP, Ceramide EOP, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hydroxyethyl Urea, Panthenol, Cetearyl Alcohol, Squalane, Carbomer, Butyrospermum Parkii (Shea) Butter, Tromethamine, Xanthan Gum, Allantoin, Ethylhexylglycerin, Adenosine, Disodium EDTA, Cyanocobalamin, 2,3-Butanediol, Dipropylene Glycol, Caprylyl Glycol, Rubus Fruticosus (Blackberry) Fruit Extract, Vaccinium Macrocarpon (Cranberry) Fruit Extract, Vaccinium Angustifolium (Blueberry) Fruit Extract, Rubus Idaeus (Raspberry) Fruit Extract, Sambucus Nigra Fruit Extract, Punica Granatum Fruit Extract, Polyglyceryl-10 Laurate, Octyldodecanol, Polyglyceryl-4 Caprate, Glyceryl Stearate, Methylpropanediol, Cholesterol, Pentylene Glycol, Astaxanthin
The small white beads are ceramide cream, set into the serum so they melt in as you apply it.
For external use only. Avoid contact with eyes. Stop use if irritation occurs.
Shipping and returns
Free US shipping on every bundle. Orders leave the next business day.
Try it for 30 days. If you don’t love how your skin looks, email us and we’ll refund you in full.
Look at how others are loving the Avena NAD+ Serum
Real women, real photos, in their own words.
Denise, Tampa FL
“I’d given up on my chest. I woke up every morning to lines I could feel. These photos are three weeks apart, no filter on either one. My husband asked what I’d changed.”
Linda, Columbus OH
“The backs of my arms went crepey in one summer. Six weeks on this, I wore a tank top to my niece’s barbecue and didn’t think about it once.”
What to expect when you start
Put it on your neck, chest and arms every day and the change comes faster than you’d think.
Day 1
Soft, not sticky
It soaks in within seconds. Your skin feels hydrated and you can get dressed straight away.
Day 7
Smoother to the touch
Run your hand up your neck. The dry, crinkly feel is already fading.
Day 21
The crepey look softens
The fine lines on your neck and chest look shallower. You notice it in the morning mirror.
Day 43
You stop hiding it
You wear the V-neck, the sleeveless top, your hair up. Your neck finally matches your face.
The internet can’t stop talking about Avena’s NAD+ Serum
Real talk from the comments 👇
Unfiltered comments from women who tried it, and what changed for them.
Tammy Richter · 3d
Has anyone actually tried the Avena NAD+ serum on their neck? Mine went crepey out of nowhere this year and I have a whole drawer of creams that did nothing. Honest answers please, not ads 🙏
Reply14
Gloria Mendez · 3d
Tammy Richter Yes! I use it on my neck and chest every night. I was the biggest skeptic. Around week 3 the lines under my chin looked softer. My daughter noticed before I said anything.
Reply11
Tammy Richter · 3d
Gloria Mendez is it greasy? I hate anything that gets on my shirts
Reply2
Gloria Mendez · 2d
Tammy Richter not at all, it soaks in in seconds. I put it on and get dressed right away.
Reply6
Sue Ellen Parker · 2d
Not gonna lie I rolled my eyes when my sister sent me this 😂 3 bottles in and my chest doesn’t look like crumpled tissue paper anymore. Arms took longer, around 6 weeks.
Reply9
Joanne Whitfield · 2d
Sue Ellen Parker same here. Neck first, arms second.
Reply3
Mark Donnelly · 1d
Bought it for my wife for her birthday because she kept wearing turtlenecks in July. She hasn’t worn one since.
Reply7
Rita Kaminski · 22h
I’m a retired dermatology nurse. Peptides, ceramides and several kinds of hyaluronic acid in one light serum is exactly what I’d look for. Been using it 8 weeks on my neck, no irritation.
Reply8
Tammy Richter · 20h
Rita Kaminski thank you, that’s really reassuring. Ordering the 28-day one tonight
Reply1
Pam Oduya · 9h
Week 4. My neck looks smoother and I did NOT expect my hands to look better too 🤞
Reply4
What makes it different
(and why it works)
Six things your body lotion doesn’t do.
01
Made for the skin below your face
Neck, chest and arms get thinner and drier first, and most creams are made for cheeks.
02
14 peptides, not one
Most firming creams lean on one or two. Fourteen work together on the look of firmness.
03
5 ceramides
They help your skin hold on to moisture, so it doesn’t dry back into crinkles by lunchtime.
04
8 forms of hyaluronic acid
Different sizes reach different layers of the skin, for a plumper, smoother look.
05
NAD+
A coenzyme your skin already uses, to help tired-looking skin look fresh again.
06
Weightless
No greasy film, nothing on your collar. It’s gone in seconds.
Finally, a serum for below your jaw.
A light serum you’ll actually use every day, made for crepey skin.
Smoother-looking neck and chest in weeksThe fine crinkles look softer with daily use. Most women see it around week three.
14 peptides, 5 ceramides, 8 hyaluronic acidsA full formula, not one hero ingredient.
Soaks in within secondsNo greasy layers, no special order of steps. Three drops and get dressed.
30 days to decide, or your money backTry it for 30 days. If you don’t love how your skin looks, email us and we’ll refund you in full.
Why does crepey skin show up on your neck first?
The skin on your neck, chest and the backs of your arms is thinner than the skin on your face.
It also makes less of its own oil, so it dries out faster.
For years that skin got sun and no care. Every cream went on your face and stopped at your jaw.
When thin, dry skin loses its bounce, it folds into fine crinkles, like crepe paper. That’s why it seems to show up in one summer.
Body lotion only sits on top. It softens the skin for an hour, then it dries out again.
Avena’s NAD+ Serum gives that skin what it’s missing: peptides for firmness, ceramides to hold moisture in, and hyaluronic acid to plump it.
Not all firming creams are created equal
How Avena’s NAD+ Serum compares with a regular firming or crepe cream.
| Avena NAD+ | Regular cream | |
|---|---|---|
| 14 peptides for the look of firmness | ||
| 5 ceramides for the moisture barrier | ||
| 8 forms of hyaluronic acid | ||
| NAD+ | ||
| Soaks in within seconds, never greasy | ||
| Made for neck, chest and arms |
30-Day Money-Back Guarantee
We know how it feels to buy another cream that does nothing. So try it for 30 days. If you don’t love how your skin looks, email us and we’ll refund you in full.
100% satisfaction
Free US shipping
Easy returns
Customer Reviews
4.8 out of 5
Based on 13,286 reviews
84%
12%
2%
1%
1%
K
09/25/2026
Karen, Scottsdale AZ
My neck matches my face again
I spent a small fortune on neck creams at the drugstore and none of them did anything I could see. Three weeks on this and the crinkly lines under my chin are softer. Photo is from this morning, no filter.
Was this review helpful? 👍 24👎 0
D
09/24/2026
Denise, Tampa FL
Three weeks apart
I woke up every morning to chest lines I could actually feel with my hand. These photos are three weeks apart, no filter on either. My husband asked what I’d changed before I told him.
Was this review helpful? 👍 31👎 1
L
09/22/2026
Linda, Columbus OH
Tank top at the barbecue
My arms went crepey in one summer and I hid them under cardigans for two years. Six weeks in, I wore a tank top to my niece’s barbecue and didn’t think about it once.
Was this review helpful? 👍 19👎 2
C
09/20/2026
Carol, Boise ID
My hands too
I started on my neck, then rubbed what was left on my fingers into the backs of my hands. Six weeks in, my hands look smoother and the brown spots are lighter. I didn’t expect that.
Was this review helpful? 👍 27👎 0
M
09/18/2026
Marsha, Raleigh NC
Gentle on my neck
Retinol left my neck red and peeling, so I was nervous. This hasn’t stung once, and it soaks in before I’ve finished brushing my teeth.
Was this review helpful? 👍 22👎 1
B
09/16/2026
Brenda, Plano TX
Wish I’d bought the 2-month
Four stars only because I ran out. The 28-day supply got me to the good part, around week three, and then I had to wait for more to arrive. Get the bigger one.
Was this review helpful? 👍 29👎 2
J
09/15/2026
Janet, Grand Rapids MI
Not greasy at all
I don’t do anything oily, and I have ruined good tops with neck creams. This is gone in seconds and nothing ends up on my collar.
Was this review helpful? 👍 17👎 0
P
09/13/2026
Pat, Sacramento CA
The skin by my underarm
The skin by my underarm used to bunch into little folds when I lifted my arm. Three weeks in, it looks smoother. My husband took both photos.
Was this review helpful? 👍 26👎 1
H
09/11/2026
Helen, Madison WI
Chest lines
I sleep on my side and wake up with lines across my chest. They fade faster now and they’re not as deep as they were.
Was this review helpful? 👍 15👎 2
R
09/09/2026
Rosa, San Antonio TX
The car mirror
The car mirror used to show every line on my neck. I took the first photo in the car and the second at home three weeks later. It looks smoother and my jaw looks cleaner.
Was this review helpful? 👍 33👎 0
D
09/07/2026
Debbie, Nashville TN
The only one I finished
Cheaper than every neck cream I’ve bought, and it’s the only one I’ve actually finished. On my third bottle.
Was this review helpful? 👍 21👎 1
L
09/05/2026
Lorraine, Portland OR
Arms take longer
Neck and chest looked better in about three weeks. My arms took closer to six. Four stars because I wanted it faster, but I’m staying on it.
Was this review helpful? 👍 18👎 2
S
09/03/2026
Sandra, Atlanta GA
Wore my hair up
I always wore my hair down to hide my neck. I wore it up to my cousin’s wedding last weekend and took a picture with it up. First time in years.
Was this review helpful? 👍 25👎 0
M
09/01/2026
Maureen, Edison NJ
One step
I don’t have the patience for routines. Three drops, sweep up the neck, done. I actually keep doing it, which is the whole point.
Was this review helpful? 👍 20👎 1
B
08/29/2026
Barb, Phoenix AZ
My daughter noticed
She asked what I’d done to my neck. I told her nothing, then showed her the bottle. She took one home.
Was this review helpful? 👍 23👎 2
G
08/27/2026
Gail, Denver CO
V-necks again
I’d bought nothing but high necks for three years. Two months in, I bought two V-neck tops and wore one to church.
Was this review helpful? 👍 30👎 0